Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3 family pseudogene

ENSG00000225720 encodes a pseudogene belonging to the apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3 (APOBEC3) family[5]. Pseudogenes are typically non-functional sequences resembling protein-coding genes but lacking the ability to encode functional proteins, usually due to mutations, truncations, or absence of regulatory elements[2][4][6]. Processed (retrotransposed) pseudogenes like this one are created when mRNA from a functional gene is reverse-transcribed and inserted back into the genome[2][4][6]. While most pseudogenes do not produce active RNA or protein products, a minority can play regulatory roles in gene expression (via microRNA decoys, for example), but no such function has been described for ENSG00000225720[6]. This locus is not considered a therapeutic target, does not encode a protein, and has no known role in signaling, transport, or disease as a direct drug target[5].

Other names

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3 pseudogeneAPOBEC3 family pseudogeneGC22P039487 (and other historical GeneCards IDs)