Target intelligence / Profile preview

Arsenic Ion

Molecular classification
Inorganic Ion
01

Overview

The arsenic ion refers to the ionic forms of the element arsenic (As), most commonly encountered as arsenic(3+) (As³⁺). Inorganic forms of the arsenic ion are highly toxic due to their ability to disrupt cellular respiration by inhibiting essential enzymes. Chronic exposure can lead to various health issues including cancer. While historically used as poisons and insecticides, some organoarsenic compounds have medicinal applications.

Other names
Arsenic(3+)Arsenic cation (3+)As³⁺Arsenic IIIArsenite (AsO₃³⁻)Arsenate (AsO₄³⁻)
02

Mechanism of action

Inhibits enzymes by binding to thiol groups, disrupts ATP production, induces oxidative stress.

03

Biological functions

Enzyme inhibitionDisruption of cellular respirationOxidative stress induction
04

Disease associations

Arsenic poisoningCancerDevelopmental toxicity
05

Safety considerations

High toxicityCarcinogenicityEnvironmental contamination
06

Interacting drugs

Chelating agents (e.g., dimercaprol)

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