Target intelligence / Profile preview

Ascorbic Acid Metabolism Pathway (N/A)

Target
N/A
Molecular classification
Metabolic Pathway
01

Overview

The ascorbic acid metabolism pathway encompasses the biosynthesis, recycling, degradation, and transport of ascorbic acid (vitamin C). Ascorbic acid is a vital antioxidant and enzyme cofactor. While most plants and many animals can synthesize ascorbic acid endogenously, humans lack this ability, requiring dietary intake. The pathway involves several key steps including oxidation/reduction reactions to neutralize ROS, transport across cell membranes, and synthesis from precursor molecules. It plays a crucial role in maintaining cellular redox balance and supporting various physiological functions.

Other names
Vitamin C MetabolismAscorbate MetabolismL-Ascorbic Acid Metabolism
02

Mechanism of action

N/A (Metabolic pathway, not a single target)

03

Biological functions

Antioxidant DefenseEnzyme Cofactor ProvisionRedox RegulationNutrient MetabolismPlant Growth and DevelopmentPhotosynthetic Electron Transport Protection (Plants)
04

Disease associations

Scurvy (Vitamin C Deficiency)Cancer (Potential Role in Prevention/Treatment)Cardiovascular Disease (Potential Role in Prevention)Neurodegenerative Diseases (Potential Role in Prevention)Oxidative Stress-Related Diseases
05

Safety considerations

High doses of ascorbic acid can cause gastrointestinal distress, kidney stones, and iron overload in susceptible individuals.Potential interactions with certain medications (e.g., warfarin).False positive glucose readings in some diabetes tests.
06

Interacting drugs

None (Pathway itself is not directly targeted, but influences drug metabolism and efficacy)

2 more in the full profile.

07

Biomarkers

Plasma Ascorbic Acid LevelsUrinary Ascorbic Acid ExcretionTissue Ascorbic Acid Concentration

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