Target intelligence / Profile preview

Asparagine (Asn)

Target: Asn
Molecular classification: Amino Acid, Non-essential Amino Acid, Aliphatic Amino Acid

Overview

Asparagine is a non-essential, polar, aliphatic α-amino acid used in the biosynthesis of proteins. It plays a key role in protein synthesis and nitrogen metabolism, particularly important for rapidly dividing cells such as cancer cells which often require increased amounts of this amino acid. In cell culture, L-asparagine supports healthy growth but should be freshly added to avoid toxic ammonia accumulation from deamination.

Other names: L-Asparaginealpha-Aminosuccinamic acidAspartamic acid β-amide

Biological functions

Protein synthesisNitrogen metabolismCell growth (in cell culture)

Disease associations

Cancer (potential requirement for rapidly dividing cells)

Safety considerations

Toxic ammonia accumulation from deamination in cell culture

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