ATPase, aminophospholipid transporter, class I, type 8 pseudogene

This entry represents a **pseudogene** related to the ATPase, aminophospholipid transporter family (class I, type 8). Within this gene family, functional homologs (e.g. ATP8A1, ATP8A2, ATP8B3) encode enzymes known as P4-ATPases that maintain membrane phospholipid asymmetry by translocating aminophospholipids across cell membranes[2][5][6]. Pseudogenes are generally *non-functional* genomic regions, derived from ancestral or related protein-coding genes, and do not encode active proteins, have no direct biological function, and are not considered druggable targets or disease loci[1]. This is **not a therapeutic target**—it is a pseudogene, not a receptor, enzyme, or active transporter. There is a risk of confusion with functional genes in the same family, such as **ATP8A1**, **ATP8A2**, or **ATP8B3**. These functional versions are involved in key cellular processes and are associated with neurological diseases, but the pseudogene itself does not have these properties[2][3][5][6]. There is **no evidence** that this pseudogene is associated with drugs, mechanisms of action, biomarkers, or known disease roles. For this entry (ENSG00000267630), it is strictly a pseudogene and is *not* actionable as a target.

Other names

ATP8A1 pseudogeneATP8A2 pseudogeneaminophospholipid-transporting ATPase pseudogeneATPase class I type 8 pseudogene