ATPase H+ transporting V1 subunit G1 pseudogene 1 (ATP6V1G1P1)

ATPase H+ transporting V1 subunit G1 pseudogene 1 (ATP6V1G1P1) is a human pseudogene derived from a gene encoding a subunit of the vacuolar ATPase (V-ATPase) complex which is responsible for acidifying intracellular compartments in eukaryotic cells. Pseudogenes like ATP6V1G1P1 contain sequence similarities to their protein-coding counterparts but have acquired disabling mutations (such as premature stop codons or frameshifts), resulting in loss of protein-coding ability. While most pseudogenes are considered nonfunctional, recent research suggests they can have regulatory roles through noncoding RNA, but there is no specific evidence that ATP6V1G1P1 itself is a therapeutic target, biomarker, or interacts with drugs. It is not a functional enzyme, receptor, transporter, nor known therapeutic target. There is no evidence it is misspelled or otherwise incorrectly designated; the entry is valid as a pseudogene. ATP6V1G1P1 does not produce protein and is not considered a molecular target in pharmacology or drug development. In general, pseudogenes can sometimes act through RNA-mediated mechanisms (e.g., as RNA decoys or small RNA sources), but no specific roles are recorded for ATP6V1G1P1 to date.

Other names

ATP6V1GP1ATPase H+ transporting, lysosomal 13kDa, V1 subunit G1 pseudogene 1