Target intelligence / Profile preview

ATPase H+ transporting V1 subunit G1 pseudogene 4 (ATP6V1G1P4)

Target
ATP6V1G1P4
Molecular classification
Other (Pseudogene)
01

Overview

ATPase H+ transporting V1 subunit G1 pseudogene 4 (ATP6V1G1P4) is a human pseudogene related to the gene encoding a subunit of the vacuolar ATPase (V-ATPase), which plays a role in acidifying intracellular organelles in eukaryotic cells[3]. As a pseudogene, ATP6V1G1P4 does not encode a functional protein. Most pseudogenes, including ATP6V1G1P4, arise from duplication or retrotransposition events and typically acquire disabling mutations that prevent them from being translated into functional proteins[1]. Some pseudogenes, in general, may regulate their parent or related genes via noncoding RNA mechanisms, such as acting as competitive endogenous RNAs (ceRNAs) or microRNA “decoys,” which can have downstream regulatory effects in cellular biology and disease, including cancer—but there is no current evidence that ATP6V1G1P4 itself serves this function[1][5].

Other names
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 pseudogene 4ATP6V1G1P4
02

Mechanism of action

Not applicable (see note below)

03

Biological functions

Potential regulator of gene expression via noncoding RNA mechanisms such as microRNA decoy or production of small interfering RNAs (siRNAs), based on the general function of pseudogenes[1][5].
04

Disease associations

Other (No direct evidence for ATP6V1G1P4, but related pseudogenes can have regulatory effects in diseases, especially cancer, via microRNA sponge or decoy effects[1][5]).

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