Axon Guidance Proteins (None)

Axon guidance proteins are a diverse group of molecules that direct the growth and navigation of neuronal axons during neural development. They act as attractants or repellents, guiding axons to their correct targets and ensuring the formation of precise neural circuits. These proteins include Netrins, Slits, Ephrins, Semaphorins, and Cell Adhesion Molecules (CAMs), each interacting with specific receptors to activate intracellular signaling cascades that modulate cytoskeletal dynamics and growth cone motility. While primarily known for their role in development, some axon guidance proteins continue to influence synaptogenesis and cell migration in the mature nervous system. Dysregulation of these proteins has been implicated in various neurological disorders.

Other names

Axon Guidance MoleculesNeuronal Guidance Cues

Modulation of growth cone motility via receptor-mediated signal transduction pathways that regulate cytoskeletal dynamics and cell adhesion.