Bacterial cell wall peptidoglycan ()

Bacterial cell wall peptidoglycan Overview

Peptidoglycan is a complex, mesh-like polymer that forms the primary structural component of most bacterial cell walls. It is composed of alternating N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc) sugars, cross-linked by short peptide chains. It provides mechanical strength, maintains cell shape, and protects bacteria from osmotic lysis. Its biosynthesis is a major target for antibiotics.

Mechanism of Action

Inhibition of peptidoglycan synthesis (e.g., transpeptidase inhibition by β-lactams, preventing cross-linking)

Biological Functions

Safety Considerations

Interacting Drugs