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Bacterial proteins from Cutibacterium acnes (formerly Propionibacterium acnes) are a diverse set of molecules, including enzymes, adhesins, and other secreted factors, that contribute to the bacterium's role as both a commensal organism and an opportunistic pathogen. These proteins are implicated in acne vulgaris, implant-associated infections, and other inflammatory conditions. Certain secreted proteins contribute to host tissue breakdown and inflammatory responses, making them potential therapeutic targets. Variations in strain-specific secreted factors such as putative adhesins influence virulence properties.
Antibiotic; inhibition of bacterial protein synthesis/cell wall synthesis/DNA replication
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