Molecular Classification
Bacteria, Gram-negative bacteria, Obligate anaerobe, Bacteroidetes
Other Names
Oral Bacteroides, Bacteroides fragilis, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides vulgatus, Bacteroidetes
Disease Roles
Bacteroides species Overview
Bacteroides species are Gram-negative, obligate anaerobic bacilli that are a significant component of the human microbiota, commonly found in the oral cavity. They play roles in maintaining ecological balance within biofilms and help break down complex molecules. While generally beneficial, they can become opportunistic pathogens if they translocate to sterile sites. Bacteroides exhibit high levels of antibiotic resistance.
Mechanism of Action
Biological Functions
Nutrient breakdown
Biofilm formation
Ecological balance in microbiome
Modulation of host immune response
Fermentation
Disease Associations
Periodontitis
Caries
Abscesses (opportunistic)
Bacteremia (opportunistic)
Infections (opportunistic)
Safety Considerations
- Antibiotic resistance
- Opportunistic infections
- Potential for virulence factors
Interacting Drugs
Antibiotics (multiple resistance mechanisms)