Bile duct (null)

Bile duct Overview

The **bile duct** system comprises a branching network of tubes that transport bile from the liver and gallbladder to the duodenum (small intestine)[1][3][5][9]. The network is collectively termed the **biliary tree** and includes intrahepatic ducts (within the liver) and extrahepatic ducts (outside the liver), such as the right and left hepatic ducts, common hepatic duct, cystic duct, and common bile duct. The main biological function is to channel bile—a digestive fluid produced by the liver and stored in the gallbladder—that is essential for digesting fats and absorbing fat-soluble vitamins[1][3][5][9]. Diseases involving the bile ducts, such as cholangiocarcinoma (bile duct cancer), cholangitis (duct inflammation), obstruction, and congenital defects, are significant causes of hepatobiliary morbidity. The bile ducts themselves are not receptors, enzymes, or molecular targets, but rather anatomical structures lined by cholangiocytes (specialized epithelial cells)[7]. Emerging cancer therapies may target molecular alterations in the epithelial cells lining the ducts in diseases like cholangiocarcinoma, but not the duct as a molecular entity[2][4][6].

Mechanism of Action

Biological Functions

Safety Considerations

Associated Biomarkers