Gosset Blood plasma water content Overview
Blood plasma water content refers to the percentage of water in blood plasma, which normally ranges from about 90% to 93% depending on the source[1][2][3][5][7][8][10]. Blood plasma is the liquid, cell-free component of blood and makes up approximately 55% of total blood volume. It contains water, proteins (albumin, globulins, fibrinogen), electrolytes, nutrients, hormones, and metabolic wastes. The high water content is crucial for dissolving and transporting these molecules throughout the body, maintaining proper blood pressure and osmotic balance, enabling normal organ function, and assisting in waste elimination. Abnormal plasma water content can result from dehydration, fluid overload, altered protein/lipid concentration, or disease and may impact laboratory test results, especially sodium measurement[3]. The term "blood plasma water content" is a physiological measurement rather than a druggable target and is not classified as a molecule, receptor, enzyme, transporter, or protein. Any use as a target is incorrect and unrelated to therapeutic targeting in molecular pharmacology.
Mechanism of Action
Biological Functions
Disease Associations
Safety Considerations
- Risk of dehydration (low plasma water content)
- Risk of fluid overload (high plasma water content)
- Laboratory errors in sodium measurement due to abnormal plasma composition
Associated Biomarkers
| Biomarker |
|---|
| Plasma osmolality |
| Serum sodium |
| Hematocrit |
| Total plasma protein |
| Volume status indicators |