Gosset Molecular Classification
Proteins, Albumin, Globulins, Fibrinogen, Enzymes, Hormones, Immunoglobulins
Other Names
Plasma Proteins, Serum Proteins
Disease Roles
Blood Proteins Overview
Blood proteins, also known as plasma proteins, are a diverse group of proteins present in the blood plasma. They play essential roles in maintaining physiological balance and supporting various bodily functions, including transport, immunity, and coagulation. Major types include albumin, globulins, and fibrinogen. Abnormal levels can indicate various diseases.
Mechanism of Action
Varies depending on specific protein and drug. Examples include: Albumin - binding and transporting drugs; Fibrinogen - inhibition of clotting; Immunoglobulins - neutralization of pathogens.
Biological Functions
Osmotic pressure regulation
Transport
Immune defense
Blood clotting
Enzymatic activity
Hormone signaling
Disease Associations
Malnutrition
Liver disease
Kidney disease
Inflammation
Infection
Cancer
Autoimmune disorders
Cardiovascular Disease
Safety Considerations
- Hypersensitivity reactions (e.g., to therapeutic antibodies)
- Drug-protein binding interactions affecting drug efficacy or toxicity
- Risk of thrombosis or bleeding (related to clotting factors)
- Liver or kidney toxicity (related to protein metabolism)
Interacting Drugs
Warfarin
Associated Biomarkers
| Biomarker |
|---|
| Total protein |
| Albumin |
| Globulin fractions (alpha, beta, gamma) |
| Albumin/Globulin ratio |
| Specific immunoglobulins (e.g., IgG, IgA, IgM) |
| Fibrinogen |