Molecular Classification
Other (Muscle tissue)
Other Names
Intestinal smooth muscle, Gastrointestinal smooth muscle
Disease Roles
Gastrointestinal disorders (e.g., irritable bowel syndrome, bowel obstruction)Inflammation

Bowel smooth muscle Overview

Bowel smooth muscle refers to the smooth muscle tissue found in the walls of the intestines. It plays a crucial role in the movement of food through the digestive tract via peristalsis and segmentation. This muscle type is involuntary and is regulated by the autonomic nervous system and various hormones and neurotransmitters. It is not a specific molecular target but rather a type of tissue involved in various physiological processes and diseases.

Mechanism of Action

Drugs may act by altering calcium ion flow, affecting neurotransmitter release, or modulating smooth muscle contraction.

Biological Functions

Muscle contraction
Peristalsis
Segmentation
Transport of substances through the digestive tract

Disease Associations

Gastrointestinal disorders (e.g., irritable bowel syndrome, bowel obstruction)
Inflammation

Safety Considerations

  • Side effects of drugs affecting bowel smooth muscle can include constipation, diarrhea, or changes in bowel habits.

Interacting Drugs

anticholinergics
antispasmodics
laxatives

Associated Biomarkers

Biomarker
None specific to bowel smooth muscle itself, but biomarkers for related conditions may exist.