Molecular Classification
Other (Muscle tissue)
Other Names
Intestinal smooth muscle, Gastrointestinal smooth muscle
Disease Roles
Bowel smooth muscle Overview
Bowel smooth muscle refers to the smooth muscle tissue found in the walls of the intestines. It plays a crucial role in the movement of food through the digestive tract via peristalsis and segmentation. This muscle type is involuntary and is regulated by the autonomic nervous system and various hormones and neurotransmitters. It is not a specific molecular target but rather a type of tissue involved in various physiological processes and diseases.
Mechanism of Action
Drugs may act by altering calcium ion flow, affecting neurotransmitter release, or modulating smooth muscle contraction.
Biological Functions
Muscle contraction
Peristalsis
Segmentation
Transport of substances through the digestive tract
Disease Associations
Gastrointestinal disorders (e.g., irritable bowel syndrome, bowel obstruction)
Inflammation
Safety Considerations
- Side effects of drugs affecting bowel smooth muscle can include constipation, diarrhea, or changes in bowel habits.
Interacting Drugs
anticholinergics
Associated Biomarkers
| Biomarker |
|---|
| None specific to bowel smooth muscle itself, but biomarkers for related conditions may exist. |
Gosset