Gosset Molecular Classification
Other, small molecule, dietary supplement ingredient
Other Names
Calcium HMB, Calcium 3-hydroxy-3-methylbutyrate, Butanoic acid, 3-hydroxy-3-methyl-, calcium salt, HMB-Ca, Calcium β-hydroxy β-methylbutyrate
Disease Roles
Calcium beta-hydroxy-beta-methylbutyrate Overview
Calcium beta-hydroxy-beta-methylbutyrate is the calcium salt form of beta-hydroxy-beta-methylbutyric acid (HMB), a naturally occurring metabolite of the amino acid leucine. As a dietary supplement, it is used to support muscle preservation and recovery, notably in sports nutrition or conditions causing muscle wasting. It is not a biological macromolecule, receptor, enzyme, transporter, or conventional drug target. Supplementation provides bioavailable HMB, which may modulate protein metabolism, but the compound itself is not a recognized molecular target for therapeutic drugs[1][2][4][5].
Mechanism of Action
Biological Functions
Other
nutritional supplement
muscle metabolism modulator via indirect metabolite effects
Disease Associations
Other
sports nutrition
muscle wasting disorders
not a direct therapeutic molecular target for major disease classes
Safety Considerations
- Gastrointestinal tolerance in high doses
- possible mineral imbalances with excess calcium intake
- typical for supplements