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Target intelligence / Profile preview
Cap-specific mRNA (nucleoside-2-O-) methyltransferase 2 (CMTR2)
- Target
- CMTR2
- Molecular classification
- Enzyme, Methyltransferase
01
Overview
Cap-specific mRNA (nucleoside‑₂′‑O-) methyltransferase II (CMTR₂) is an essential mammalian enzyme responsible for adding a key chemical mark (“cap ₂” structure) onto messenger RNAs after transcription. This mark helps protect transcripts from degradation and modulates their recognition by cellular machinery involved in translation initiation and immune surveillance.
- Other names
- Cap methyltransferase 2FTSJD1MTr2HMTr2
02
Biological functions
mRNA processingmRNA stabilityEvasion of innate immune detectionTranslation initiationTranscript maturation
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