Carboxypeptidase X, M14 family member 1 (CPXM1)

Carboxypeptidase X, M14 family member 1 (CPXM1) is a protein in humans encoded by the CPXM1 gene[7][4][2]. It belongs to the M14 family of zinc-dependent carboxypeptidases and structurally contains a discoidin domain and a carboxypeptidase domain[4]. However, unlike typical carboxypeptidase enzymes, CPXM1 lacks key residues necessary for carboxypeptidase activity and has no detectable enzymatic function[4][2][7]. Evidence suggests CPXM1 is involved in cell-cell interactions and is thought to be an extracellular or cell membrane protein[2][4]. Mutations or altered expression of CPXM1 have been associated with human diseases such as mirror movements 1 and gastric diffuse adenocarcinoma[4]. Currently, no drugs are known to interact with CPXM1, and there are no validated clinical biomarkers or specific safety concerns connected to its modulation. The function of CPXM1 remains incompletely understood, but its structural family places it among metallocarboxypeptidase-like proteins without classical enzymatic activity[7][2][4].

Other names

Probable carboxypeptidase X1CPXM1CPX1CPXMUNQ3015/PRO9782CPX-1carboxypeptidase-like protein X1metallocarboxypeptidase CPX-1