Cariogenic Bacteria Metabolism Pathway (Streptococcus mutans)

The cariogenic bacteria metabolism pathway, primarily associated with *Streptococcus mutans*, is the process by which these bacteria metabolize dietary sugars, especially sucrose, into organic acids, mainly lactic acid. This acid production leads to the demineralization of tooth enamel and the development of dental caries. The pathway involves efficient sugar uptake via PTS and ABC transporters, glycolysis for energy production, extracellular polysaccharide synthesis for biofilm formation, and tight regulation of gene expression based on substrate availability. This metabolic flexibility enables *S. mutans* to thrive in the oral environment and contribute to the progression of dental caries.

Other names

Streptococcus mutans carbohydrate metabolismDental caries metabolic pathwayAcidogenesis in oral biofilms

Fluoride inhibits bacterial glycolysis, reducing acid production. Antibiotics kill or inhibit bacterial growth. Sugar substitutes are poorly metabolized by cariogenic bacteria. Probiotics compete for resources and space in the oral cavity.