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Target intelligence / Profile preview
Caspase recruitment domain family member 17, pseudogene (CARD17P)
- Target
- CARD17P
- Molecular classification
- Pseudogene
01
Overview
Caspase recruitment domain family member 17, pseudogene (CARD17P) is a human gene locus annotated as a pseudogene, meaning it does not encode a functional protein product. Although several aliases suggest a role in inflammation and caspase-1 inhibition, these descriptions reflect inferred functions from related proteins rather than this gene itself. The locus has been given approved nomenclature by the Human Gene Nomenclature Committee (HGNC:33827), and alternative names may refer to functional homologs or pseudogenized ancestral proteins. As a pseudogene, CARD17P is not considered a druggable molecular target, and there are no defined biological functions, disease associations, interacting drugs, or safety concerns directly attributable to it.
- Other names
- Putative caspase recruitment domain-containing protein 17PCARD17PCARD17INCACaspase-1 inhibitor INCAInhibitory caspase recruitment domain proteinInhibitory CARD
02
Mechanism of action
Not applicable. No drugs target CARD17P
03
Biological functions
None confirmed, as CARD17P is a pseudogeneFunctional descriptions attached to some aliases (such as inhibition of caspase-1 or IL1B regulation) relate to functional homologs but not CARD17P per se
04
Disease associations
No direct roles established; although some disease association databases list links (e.g., Tuberculous Empyema), these associations are indirect and may reflect proximity or assumptions rather than functional evidenceThe mention of cellular response to lipopolysaccharide and regulation of interleukin-1 beta production are based on inferred or hypothetical protein function, but as a pseudogene CARD17P itself is not implicated
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