Molecular Classification
Endocytosis pathway, Cellular transport pathway
Disease Roles
Cancer progression/metastasisCardiovascular diseaseMuscular dystrophy

Caveolae-mediated endocytosis pathway Overview

Caveolae-mediated endocytosis is a clathrin-independent cellular uptake mechanism involving small, flask-shaped invaginations of the plasma membrane called caveolae. These structures are typically 50–60 nm in diameter and are rich in cholesterol, sphingolipids, and specific proteins such as caveolins and cavins. This pathway operates parallel to clathrin-mediated endocytosis but is more selective and highly regulated, often triggered by ligand binding.

Mechanism of Action

N/A

Biological Functions

Cellular uptake
Signal transduction regulation
Lipid homeostasis
Pathogen entry

Disease Associations

Cancer progression/metastasis
Cardiovascular disease
Muscular dystrophy
Viral infections
Bacterial infections

Safety Considerations

No safety concerns listed