Molecular Classification
Endocytosis pathway, Cellular transport pathway
Disease Roles
Caveolae-mediated endocytosis pathway Overview
Caveolae-mediated endocytosis is a clathrin-independent cellular uptake mechanism involving small, flask-shaped invaginations of the plasma membrane called caveolae. These structures are typically 50–60 nm in diameter and are rich in cholesterol, sphingolipids, and specific proteins such as caveolins and cavins. This pathway operates parallel to clathrin-mediated endocytosis but is more selective and highly regulated, often triggered by ligand binding.
Mechanism of Action
N/A
Biological Functions
Cellular uptake
Signal transduction regulation
Lipid homeostasis
Pathogen entry
Disease Associations
Cancer progression/metastasis
Cardiovascular disease
Muscular dystrophy
Viral infections
Bacterial infections
Safety Considerations
No safety concerns listed