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Caveolae-mediated endocytosis pathway (None)

Target: None
Molecular classification: Endocytosis pathway, Cellular transport pathway

Overview

Caveolae-mediated endocytosis is a clathrin-independent cellular uptake mechanism involving small, flask-shaped invaginations of the plasma membrane called caveolae. These structures are typically 50–60 nm in diameter and are rich in cholesterol, sphingolipids, and specific proteins such as caveolins and cavins. This pathway operates parallel to clathrin-mediated endocytosis but is more selective and highly regulated, often triggered by ligand binding.

Mechanism of action

N/A

Biological functions

Cellular uptakeSignal transduction regulationLipid homeostasisPathogen entry

Disease associations

Cancer progression/metastasisCardiovascular diseaseMuscular dystrophyViral infectionsBacterial infections

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