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Target intelligence / Profile preview
CD36 molecule (CD36 blood group)
- Molecular classification
- CD molecules, Integral membrane glycoprotein, Scavenger receptor
01
Overview
CD36 is an integral membrane glycoprotein acting as a scavenger receptor for various ligands, including thrombospondin-1, long-chain fatty acids, modified LDL, DAMPs, and PAMPs. It plays roles in fatty acid uptake, angiogenesis regulation, immune responses, and lipid metabolism.
- Other names
- Collagen type I receptorThrombospondin receptorPlatelet glycoprotein 4SCARB3Fatty acid translocase (FAT)
02
Biological functions
Immune responseFatty acid uptake and transportLipid metabolismAngiogenesis regulationPathogen recognitionApoptotic cell clearance
03
Disease associations
AtherosclerosisObesityDiabetesTumor progression
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