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Cellular Immune System (CD4 and CD8 T Lymphocytes) (N/A)
- Target
- N/A
- Molecular classification
- Cell
01
Overview
The cellular immune system is primarily composed of T lymphocytes, specifically CD4+ helper T cells and CD8+ cytotoxic T cells. These cells play critical roles in adaptive immunity, orchestrating immune responses and directly killing infected or cancerous cells. CD4+ T cells recognize exogenous antigens presented by MHC class II molecules and orchestrate immune responses by activating B-cells, supporting phagocytosis, and providing help to CD8+ T-cells. CD8+ T cells recognize endogenous antigens presented by MHC class I molecules and directly kill infected or cancerous target cells.
- Other names
- T lymphocytesCD4+ T cellsCD8+ T cellsHelper T cellsCytotoxic T cellsKiller T cells
02
Mechanism of action
N/A
03
Biological functions
Adaptive immunityImmune responseAntigen recognitionCytokine productionTarget cell killingB cell activationPhagocytosis supportMemory cell formation
04
Disease associations
ImmunodeficiencyCancerInfectionAutoimmunity
05
Safety considerations
ImmunodeficiencyAutoimmunityCytokine storm
06
Interacting drugs
Checkpoint inhibitors
4 more in the full profile.
07
Biomarkers
CD4 expressionCD8 expressionCytokine profiles
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