Chromosome 12 open reading frame 71B, pseudogene (C12orf71BP)

C12orf71BP (chromosome 12 open reading frame 71B, pseudogene) is a human pseudogene located on chromosome 12[1][2]. Pseudogenes are genomic DNA sequences resembling functional genes but typically contain disabling mutations (such as frameshifts or premature stop codons), which prevent them from encoding functional proteins. They may arise through various mechanisms, including duplication and mutation or retrotransposition[4]. While some pseudogenes are transcribed into RNA and may have regulatory effects on gene expression—including acting as miRNA decoys or producing small interfering RNAs—there is no specific evidence that C12orf71BP has any known function, involvement in disease, or relevance as a drug target[1][2][4]. In summary, C12orf71BP is a non-functional pseudogene with no established role as a therapeutic or research target and no known biological or clinical significance.

Other names

HGNC:56323NCBI Gene:100506578Ensembl:ENSG00000256056