Ciliary body epithelium

The ciliary body epithelium refers to two layers of epithelial cells covering the inner surface of the ciliary processes within the eye's uveal tract. These layers are known as the pigmented ciliary epithelium (PCE) and non-pigmented ciliary epithelium (NPCE). Together, they function primarily in secreting aqueous humor—the clear fluid that maintains intraocular pressure and provides nutrients for avascular ocular tissues. The NPCE is responsible for active secretion involving ion transporters such as Na⁺/K⁺ ATPase pumps and aquaporins, while tight junctions between these cells form part of the blood-aqueous barrier. The activity is regulated by autonomic innervation and hormonal factors. Dysfunction or disease affecting this epithelial layer can contribute to conditions like glaucoma or uveitis; however, "ciliary body epithelium" is an anatomical structure rather than a discrete therapeutic molecular target.

Other names

Ciliary epitheliumNon-pigmented ciliary epithelium (NPCE)Pigmented ciliary epithelium (PCE)