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Coiled-coil domain containing 162, pseudogene (CCDC162P)

Target: CCDC162P
Molecular classification: Other, Pseudogene

Overview

Coiled-coil domain containing 162, pseudogene (CCDC162P) is a human gene located on chromosome 6q21 that represents a non-coding counterpart of the mouse coiled-coil domain containing 162 gene. Although transcribed, this locus contains multiple disruptive sequence changes such as premature stop codons, causing it to be classified as a unitary pseudogene in humans. Transcripts arising from this locus are typically degraded via nonsense-mediated decay, and the encoded products—if any—are truncated and non-functional. CCDC162P is not recognized as a protein-coding gene or a functional therapeutic target. Genome-wide association studies have linked genetic variants in this region with hematological parameters and certain complex traits, but CCDC162P itself is not known to play a direct biological or disease-driving role in humans[1][4][6].

Other names: C6orf183C6orf184C6orf185CCDC162bA425D10.7bA425D10.3bA487F23.3

Biological functions

Other (no known coding function in humans; transcripts may be subject to nonsense-mediated decay)

Disease associations

Other (associated in GWAS with traits such as blood cell counts, hemoglobin levels, body height, intelligence, schizophrenia, and sleep apnea, but not considered a direct disease gene or therapeutic target)

Biomarkers

Variants in this pseudogene have been associated in genome-wide association studies (GWAS) with hematological traits and certain complex diseases; however, these serve primarily as genetic markers rather than predictive biomarkers for therapeutic efficacy[1][6].

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