Target intelligence / Profile preview

Collagen-Hyaluronan Network (Vitreous Body) (N/A)

Target
N/A
Molecular classification
Extracellular Matrix, Structural Protein, Glycosaminoglycan, Collagen, Hyaluronan
01

Overview

The collagen-hyaluronan network in the vitreous body is a specialized extracellular matrix (ECM) structure within the eye, composed of collagen fibrils interspersed with hyaluronan (hyaluronic acid, HA). It maintains ocular shape, provides biomechanical support, and acts as a clear medium for light transmission. Alterations in this network can contribute to conditions like posterior vitreous detachment or diabetic retinopathy.

Other names
Vitreous Body Extracellular MatrixCollagen-Hyaluronic Acid NetworkVitreous Humor Matrix
02

Mechanism of action

N/A

03

Biological functions

Maintains ocular shapeLight transmissionSpatial bufferNutrient diffusionBiomechanical supportHydration
04

Disease associations

Posterior Vitreous DetachmentDiabetic RetinopathyAging-related eye disorders
05

Safety considerations

Alterations can lead to changes in viscoelasticity or transparencyGlycation can stiffen collagen fibers

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