Molecular Classification
Tissue, Epithelium
Disease Roles
Colon Mucosa Overview
The colon mucosa is the innermost lining of the colon, a major part of the large intestine. It consists of three layers: epithelium, lamina propria, and muscularis mucosae. The epithelium is composed of absorptive columnar cells, mucus-secreting goblet cells, enteroendocrine cells, Paneth cells, and stem cells. The colon mucosa functions in water and electrolyte absorption, mucus secretion, barrier function against pathogens, and immune defense. It is clinically relevant in colorectal cancer, inflammatory bowel diseases, and other conditions.
Mechanism of Action
Biological Functions
Water and electrolyte absorption
Mucus secretion
Barrier function
Immune defense
Nutrient absorption
Disease Associations
Colorectal cancer
Ulcerative colitis
Crohn's disease
Polyp formation
Adenoma formation
Diverticulitis
Celiac disease
Safety Considerations
No safety concerns listed