Target intelligence / Profile preview

Colonic Bacteria

Molecular classification
Microbial Community, Bacteria
01

Overview

Colonic bacteria, also known as the colonic microbiota or gut flora of the colon, are a diverse community of microorganisms—primarily bacteria—that inhabit the large intestine (colon) in humans and other animals. These bacteria are mostly anaerobic, thriving in the low-oxygen environment of the colon. They play essential roles in digestion, metabolism, immune function, and maintaining overall gut health. Key functions include fermentation of undigested carbohydrates, nutrient synthesis (e.g., vitamins), and immune modulation. Disruption or imbalance (dysbiosis) can lead to increased susceptibility to infections and various diseases.

Other names
Colonic MicrobiotaGut Flora of the ColonGut Microbiome (Colon Specific)
02

Mechanism of action

N/A (Complex Community - Mechanisms Vary Widely Depending on Specific Bacteria)

03

Biological functions

FermentationNutrient SynthesisImmune ModulationDigestionMetabolismColonization Resistance
04

Disease associations

Inflammatory Bowel Disease (IBD)Infection (e.g., Clostridioides difficile)ObesityDiabetesAutoimmune ConditionsMental Health (Potential Influence)Ulcerative Colitis
05

Safety considerations

DysbiosisOpportunistic InfectionsPotential for harmful metabolite production (e.g., hydrogen sulfide)Antibiotic resistance transfer
06

Interacting drugs

Antibiotics

3 more in the full profile.

07

Biomarkers

Specific bacterial species abundance/diversityShort-chain fatty acid (SCFA) levelsMetabolomic profilesFecal calprotectin (as an indicator of inflammation indirectly related to bacterial composition)

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