Molecular Classification
Other (epithelial tissue)
Other Names
Conjunctival epithelial cells, Ocular surface epithelium (context-dependent)
Disease Roles
Inflammation (e.g., conjunctivitis)Infection (bacterial, viral, allergic conjunctivitis)

Conjunctival epithelium Overview

The **conjunctival epithelium** is a specialized nonkeratinized stratified squamous or columnar epithelial layer that lines the inside of the eyelids and covers the anterior sclera of the eye[1][7][8]. It is typically 2–5 cell layers thick and contains interspersed goblet cells responsible for secreting mucins essential for maintaining tear film stability and ocular surface integrity[1][6]. The conjunctival epithelium acts as a physical barrier against environmental insults such as dust, allergens, microbes, and chemicals. It also plays an important role in immune surveillance by housing lymphocytes and other immune cells within its structure[1][3]. This tissue is not a molecular target like a receptor or enzyme but rather an anatomical structure composed of various cell types. Pathological changes in this layer are associated with diseases such as conjunctivitis or dry eye syndrome[6]. **Note:** "Conjunctival epithelium" refers to an anatomical tissue type rather than a discrete molecular target; therefore it does not fit standard therapeutic target classifications such as receptor or enzyme. If you are seeking information on specific molecular targets expressed by this tissue (such as receptors on conjunctival epithelial cells), please specify further.

Mechanism of Action

Biological Functions

Physical barrier to pathogens and particles
Secretion of mucins for tear film stability
Immune surveillance and response

Disease Associations

Inflammation (e.g., conjunctivitis)
Infection (bacterial, viral, allergic conjunctivitis)

Safety Considerations

  • Susceptibility to chemical burns, infections, immune-mediated damage

Associated Biomarkers

Biomarker
Goblet cell density (for ocular surface disease assessment)