Molecular Classification
Epithelium, Stratified Squamous Epithelium
Other Names
Epithelium anterius corneae
Disease Roles
Corneal Epithelium Overview
The corneal epithelium is the outermost layer of the cornea, composed of non-keratinized stratified squamous epithelial cells. It serves as a critical barrier protecting the eye from environmental insults, pathogens, and fluid loss. This layer also plays a role in maintaining corneal transparency and contributes to ocular surface homeostasis. Damage or disease affecting this layer can result in pain, impaired vision, and increased infection risk.
Mechanism of Action
Biological Functions
Barrier function
Protection against pathogens
Maintenance of corneal transparency
Nutrient absorption
Oxygen absorption
Sensory perception
Disease Associations
Epithelial ingrowth
Recurrent corneal erosion
Infectious keratitis
Dry eye disease
Corneal wound healing
Safety Considerations
- Compromised barrier function leads to increased susceptibility to infection
- Dysfunction can impair vision
- Damage can cause pain and discomfort