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Coronin, actin binding protein, 1C pseudogene (ENSG00000257426) is a non-functional gene related to the protein-coding CORO1C gene. As a pseudogene, it does not produce protein and thus is not a direct target for pharmacological intervention or biomarker development. The functional counterpart, Coronin 1C (CORO1C), is an actin-binding protein involved in regulating the cytoskeleton, cell migration, and adhesion, and has been implicated in cancer progression and metastasis. Research focuses on the protein-coding gene CORO1C as a possible drug target and prognostic biomarker in various cancers, acting via the PI3K/AKT signaling pathway and impacting EMT and tumor cell invasiveness[1][2][4][5].
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