Target intelligence / Profile preview

CTAGE family member 12, pseudogene (CTAGE12P)

Target
CTAGE12P
Molecular classification
Other (Pseudogene)
01

Overview

CTAGE family member 12, pseudogene (CTAGE12P) is identified as a pseudogene located on human chromosome 9 (hg38: chr9:27608382-27610745)[1][3]. As a pseudogene, CTAGE12P is a genomic DNA sequence similar to a functional gene but rendered nonfunctional due to accumulated mutations that prevent proper protein coding[2][5]. CTAGE12P does not encode a protein and is not classified as a receptor, enzyme, transporter, transcription factor, or other standard molecular drug target class[1][3]. Current databases do not recognize it as a therapeutic target, and there are no reports linking it to drug interactions, mechanisms of drug action, use as a biomarker, or specific safety concerns. While pseudogenes in general can sometimes play roles in gene regulation or disease (for example, as competitive endogenous RNAs or sources of regulatory transcripts[4][5]), there is no evidence for such a function in the case of CTAGE12P. Because CTAGE12P is a pseudogene, it is not a valid drug target and should be marked as "incorrect" when validating therapeutic target lists.

Other names
CTAGE12P
02

Biological functions

Other (Typically non-functional; may play a role in gene regulation as described for some pseudogenes[4][5])
03

Disease associations

Other (No established disease role for CTAGE12P specifically; generally, some pseudogenes may regulate gene expression and could incidentally be linked to disease processes[5])

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