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Cytochrome P450 family 3 subfamily A member 54, pseudogene (CYP3A54P)
- Target
- CYP3A54P
- Molecular classification
- Pseudogene, Non-coding DNA, Cytochrome P450 superfamily (by sequence homology, not function)
01
Overview
Cytochrome P450 family 3 subfamily A member 54, pseudogene (CYP3A54P) is a human pseudogene located within the CYP3A locus on chromosome 7. It shares homology with active CYP3A genes such as CYP3A4, which are critical for the metabolism of drugs and steroids, but CYP3A54P itself does not code for a functional protein due to disabling mutations. While pseudogenes can sometimes participate in the regulation of gene expression—for example, by acting as microRNA decoys—there is no established evidence of such a role for CYP3A54P. CYP3A54P is one of four pseudogenes (CYP3A51P, CYP3A52P, CYP3A54P, CYP3A137P) associated with the CYP3A family and is not considered a therapeutic target, biomarker, or locus for drug interactions.
- Other names
- CYP3A-se1cytochrome P450, family 3, subfamily A, polypeptide 54, pseudogene
02
Mechanism of action
None (no protein product, not a drug target)
03
Biological functions
None (no known direct biological function; pseudogene)Possible regulatory role through RNA transcripts, but not specific to CYP3A54P (shown for some pseudogenes in other families)
04
Disease associations
None directly attributableSome pseudogenes act as gene expression regulators or are biomarkers in cancer or other diseases, mostly as exceptions
05
Safety considerations
None (not therapeutically targeted; no drug interactions)
06
Interacting drugs
None (no protein product, therefore no drug interaction)
1 more in the full profile.
07
Biomarkers
None known for clinical use
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