Target intelligence / Profile preview

Defensin alpha 10, pseudogene (DEFA10P)

Target
DEFA10P
Molecular classification
Pseudogene, Non-coding genetic element, Defensin gene family (pseudogene member)
01

Overview

Defensin alpha 10, pseudogene (DEFA10P) is a non-functional member of the alpha-defensin gene family found in primates. Alpha-defensins are endogenous cationic peptides involved in broad-spectrum antimicrobial defense, but DEFA10P contains sequence defects or truncations that abolish its protein-coding potential. DEFA10P shares sequence similarity with other α-defensins and is informative in studies of primate gene evolution, particularly alpha- and theta-defensin clusters, but does not contribute a functional protein to human physiology. It does not serve as a therapeutic target, nor is it implicated as a disease gene, biomarker, or drug-interaction partner.

Other names
DEFA10PDefensin, alpha 10, pseudogeneDefensin α10 pseudogene
02

Mechanism of action

None (no known mechanisms, as there is no protein expression)

03

Biological functions

The gene does not encode a protein and therefore has no biological function
04

Disease associations

Other

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