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Deoxyribonucleic Acid (DNA) (DNA)

Target: DNA
Molecular classification: Nucleic Acid

Overview

DNA is the molecule that carries genetic information in all known living organisms. As a therapeutic target, DNA can be damaged via crosslinking by various agents, leading to cell death. This is exploited in chemotherapy. DNA is also used in the development of hydrogels.

Other names: Genetic Material

Mechanism of action

Forms DNA crosslinks, inhibiting replication and transcription

Biological functions

Genetic information storageReplicationTranscriptionTemplate for protein synthesis

Disease associations

CancerGenetic disordersAging

Safety considerations

Off-target effects leading to toxicityDevelopment of drug resistance

Interacting drugs

Cisplatin

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