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Target intelligence / Profile preview
DNA polymerase catalytic subunit (HHV-1) (DPOL_HHV1)
- Target
- DPOL_HHV1
- Molecular classification
- Enzyme, DNA Polymerase
01
Overview
The DNA polymerase catalytic subunit in Human herpesvirus 1 (HHV-1, also known as herpes simplex virus type 1 or HSV-1) is a key enzyme responsible for replicating the viral genome during infection. This protein is essential for viral DNA synthesis and the production of infectious virus particles. It is a prime target for antiviral drugs, and drug resistance can develop through mutations in this protein.
- Other names
- UL30 proteinHHV-1 DNA polymerase
02
Mechanism of action
Inhibition of viral DNA polymerase activity
03
Biological functions
Viral DNA replicationDNA synthesisProofreadingGenome replication
04
Disease associations
InfectionViral infection
05
Safety considerations
Drug resistance development through mutations
06
Interacting drugs
Acyclovir
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