DNA polymerase delta 2, accessory subunit pseudogene 1 (POLD2P1)

DNA polymerase delta 2, accessory subunit pseudogene 1 (POLD2P1) is classified as a pseudogene in the human genome[4]. Pseudogenes are genomic sequences similar to known genes but are non-functional; they do not encode active proteins and typically do not have a direct biological function in normal physiology or disease. POLD2P1 resembles the protein-coding gene POLD2, which encodes part of the DNA polymerase delta complex involved in DNA replication and repair, but POLD2P1 itself does not produce a functional protein and is not considered a drug target or biomarker[4]. POLD2P1 is clearly annotated as a pseudogene in multiple gene databases[4], meaning it does not encode a functional protein and generally has no recognized biological activity or role in disease. POLD2 (not POLD2P1) is the functional gene coding for the DNA polymerase delta 2 accessory subunit[1][3][6]. There is no evidence or literature supporting POLD2P1 as a therapeutic target, disease biomarker, or drug-interacting protein. If you intended to refer to the active subunit of DNA polymerase delta (POLD2), rather than this pseudogene, please clarify, as all available evidence confirms POLD2P1 is a non-functional pseudogene and not a therapeutic or biological target.

Other names

DNA polymerase delta 2, accessory subunit pseudogene 1POLD2P1