Target intelligence / Profile preview

E2F transcription factor 1 (E2F1) (E2F1)

Target
E2F1
Molecular classification
Transcription factor
01

Overview

Other names
E2F-1Retinoblastoma-associated protein 1RBAP-1RBBP-3PBR3Transcription factor E2F1
02

Mechanism of action

Inhibition of E2F1 transcriptional activity, disruption}

03

Biological functions

Cell cycleDNA replicationApoptosisDNA repairCell proliferation
04

Disease associations

CancerSmall cell lung cancerTriple-negative breast cancerRetinoblastomaOsteosarcoma
05

Interacting drugs

CID-078

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