Target intelligence / Profile preview

EIF2A eukaryotic translation initiation factor 2A, 65kDa, pseudogene (EIF2AP2)

Target
EIF2AP2
Molecular classification
Other (pseudogene)
01

Overview

EIF2AP2 (ENSG00000271568) is a *pseudogene* corresponding to the eukaryotic translation initiation factor 2A, 65kDa. Unlike the functional EIF2A gene, pseudogenes like EIF2AP2 do not encode active proteins. Instead, pseudogenes are generally considered noncoding sequences that have lost their protein-coding potential through evolutionary processes, and therefore do not have defined protein structure, biological function, or therapeutic relevance. No evidence supports a disease role or drug targeting for EIF2AP2. Key Points & Clarifications: - Pseudogene status: The field "is_incorrect" is *true* specifically because this entry describes a pseudogene, not a targetable receptor, enzyme, transporter, or other typical drug target. - There is a functional gene **EIF2A** (eukaryotic translation initiation factor 2A), sometimes referenced similarly; however, **EIF2AP2/ENSG00000271568** refers *specifically to a pseudogene*, not the active protein[7][8]. - Pseudogenes are sometimes studied for their regulatory roles (as noncoding RNAs) but have no direct protein or pathway function[1][2].

Other names
EIF2AP2ENSG00000271568EIF2A pseudogeneeukaryotic translation initiation factor 2A pseudogene
02

Mechanism of action

None applicable (not a drug target)

03

Biological functions

None (does not encode a functional protein; pseudogenes are generally non-functional remnants of genes)
04

Disease associations

Other (pseudogenes are not typically associated with disease mechanisms; no known direct involvement in cancer, inflammation, neurodegenerative disease, etc.)
05

Safety considerations

None (not used therapeutically or as a target)
06

Interacting drugs

None (not a functional protein; not targeted by drugs)
07

Biomarkers

None known (not used for patient selection or efficacy monitoring as a biomarker)

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