Enoyl-CoA hydratase domain-containing protein 3, mitochondrial (ECHDC3)

Enoyl-CoA hydratase domain-containing protein 3, mitochondrial (ECHDC3) is a mitochondrial enzyme predicted to possess enoyl-CoA hydratase activity, which suggests a role in the hydration step of fatty acid β-oxidation and biosynthesis. It is implicated in fatty acid metabolism and regulation of cellular response to insulin, highlighting possible roles in metabolic health and disease, particularly in the context of Alzheimer disease and familial meningioma risk. ECHDC3 is expressed in many tissues, including metabolic organs and the testis, and is encoded by the ECHDC3 gene located in mitochondria. While it does not have established drug interactions or recognized biomarker roles, its function in fatty acid metabolism may make it relevant for future therapeutic intervention studies.

Other names

ECHDC3Enoyl-CoA hydratase domain containing 3Enoyl-CoA hydratase domain-containing protein 3, mitochondrialFLJ20909PP1494PP8332testis tissue sperm-binding protein Li 76menoyl Coenzyme A hydratase domain containing 3

Not well-characterized; inferred mechanisms from homologs involve hydratase activity in fatty acid metabolism and possibly modulation of insulin sensitivity. Any drug interaction mechanism would likely depend on modulation of fatty acid biosynthesis or insulin responsiveness.