Target intelligence / Profile preview

Family with sequence similarity 90 member A28, pseudogene (FAM90A28P)

Target
FAM90A28P
Molecular classification
Other (Pseudogene)
01

Overview

Family with sequence similarity 90 member A28, pseudogene (FAM90A28P), is classified as a pseudogene within the FAM90A family[1][2]. Pseudogenes are genomic DNA sequences resembling known genes but often contain mutations (e.g., frameshifts or premature stop codons) that prevent them from being translated into functional proteins[3][4]. While historically labeled as “junk DNA,” recent research shows that some pseudogenes can be transcriptionally active and may play regulatory roles in processes such as RNA interference, microRNA decoy, and gene expression modulation[3][4]. However, for FAM90A28P specifically, there is currently no direct evidence of such a role, and it is not characterized as a therapeutic target[1][2]. There are no known associated drugs, clinical biomarkers, or direct disease links.

Other names
FAM90A28PGC19M053804 (previous identifier)
02

Biological functions

Possible roles in RNA regulation and microRNA decoy, like some pseudogenes, but no specific function attributed to FAM90A28P itself
03

Disease associations

Other (No direct disease association described for FAM90A28P; pseudogenes in general can have regulatory roles relevant to cancer and other diseases but only select pseudogenes have demonstrated this)

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