Target intelligence / Profile preview

Farnesyltransferase, CAAX box, alpha pseudogene 2 (FNTAP2)

Target
FNTAP2
Molecular classification
Other (Pseudogene; not a functioning enzyme, receptor, transporter, etc.)
01

Overview

FNTAP2 is a human pseudogene related to the alpha subunit of farnesyltransferase, which functions in the transfer and posttranslational modification of isoprenoid groups to protein cysteine residues at C-terminal CAAX motifs. The functional alpha subunit (encoded by FNTA) is a key part of protein prenylation pathways important for Ras signaling and other processes in cell membrane localization, but FNTAP2 itself does not produce a protein product and has no known biological or therapeutic role[1][3][5]. If you are interested in a therapeutic target, you should use the functional gene FNTA (Farnesyltransferase, CAAX box, alpha), not the pseudogene FNTAP2[1][3][5]. The pseudogene does not encode an active protein and is not regarded as a receptor, enzyme, or drug target.

Other names
FNTAL2FNTAP2
02

Mechanism of action

None (No mechanisms, as it is not an active protein)

03

Biological functions

None (As a pseudogene, it does not encode a functional protein)
04

Disease associations

None directly known (No evidence that this pseudogene acts in disease)

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