FCF1 small subunit processome component homolog, pseudogene (FCF1P (no commonly used abbreviation for the pseudogene; "FCF1P" is an inferred abbreviation consistent with pseudogene naming conventions))

This entry refers to a **pseudogene** related to the FCF1 small subunit processome component, located at Ensembl ID ENSG00000271537. Pseudogenes are genetic loci similar to protein-coding genes but are generally non-functional due to mutations or lack of regulatory elements. The canonical FCF1 gene encodes a protein necessary for ribosomal RNA processing as part of the small subunit processome, but this pseudogene variant is not believed to produce an active protein product or serve as a therapeutic target[3][4]. **Key context and supporting details:** - The entry "FCF1 small subunit processome component homolog, pseudogene" with UID ENSG00000271537 is a pseudogene according to standard nomenclature conventions and by analogy to FCF1P1 and FCF1P7[3][4]. - Valid FCF1 (not the pseudogene) encodes an RNA-binding protein involved in ribosomal biogenesis[1][8]. The pseudogene is not expected to have this function. - There are no known therapeutic drugs, disease roles, or biomarker applications for this pseudogene. - As a pseudogene, it should not be considered a molecular drug target. Its inclusion on a list of potential drug targets is likely incorrect. **Clarification on potential confusion:** - The *functional* gene FCF1 (Ensembl: ENSG00000119616), also called FCF1 rRNA-processing protein, is distinct and encodes a ribosome biogenesis protein[1][8]. - ENSG00000271537 does not describe this functional protein but a homologous, non-functional pseudogene locus. - Some gene annotations (like FCF1P1, FCF1P7) may refer to specific pseudogene family members. No evidence exists that any are druggable or clinically relevant[3][4]. - If a therapeutic target was intended, consider confirming the Ensembl ID and gene name, as the pseudogene is not a drug target. **Summary:** This target is a pseudogene related to the ribosome biogenesis factor FCF1. Pseudogenes do not produce functional proteins and are not considered therapeutic targets. If you require information on the active FCF1 protein, reference should be made to its corresponding protein-coding gene (FCF1, ENSG00000119616)[1][8].

Other names

FCF1PFCF1P1FCF1 Pseudogene 1FCF1 Pseudogene 7 (see note below)