Fel d 1 allergen (cat) (None)

Fel d 1 is the primary allergen produced by domestic cats, responsible for the majority of allergic reactions in humans sensitive to cats. It is a tetrameric glycoprotein found in sebaceous, salivary, and anal glands, as well as fur and skin. It elicits strong IgE-mediated immune responses upon exposure, leading to symptoms ranging from mild rhinoconjunctivitis to severe asthma attacks. Therapeutic strategies target Fel d 1 to desensitize patients or modulate immune responses.

Hypoallergenic variants, peptide-based immunotherapy containing T-cell epitopes from Fel d 1, recombinant constructs coupled with immunomodulatory proteins, anti-Fel d 1 antibody-containing egg products