Ferritin heavy chain like 18, pseudogene (FTHL18P)

Ferritin heavy chain like 18, pseudogene (FTHL18P) is a processed pseudogene in the human genome and part of the ferritin multigene family, which consists of the primary ferritin heavy chain gene (FTH1), several related protein-coding genes, and over 40 pseudogenes[3][4][6]. Pseudogenes such as FTHL18P do not encode a functional protein due to disruptions in their coding sequence and generally lack significant biological function; however, some ferritin pseudogenes have been described to exert gene regulatory activity by acting as competing endogenous RNAs that modulate the expression of their parental gene (FTH1) via microRNA binding[6][7]. There is currently no evidence that FTHL18P itself is expressed as RNA or exerts any such regulatory function, in contrast to a few other ferritin heavy chain pseudogenes[3][4][6]. FTHL18P is not a therapeutic drug target or biomarker, is not linked to any known disease, and has no known protein or physiological activity in humans[3][4][6].

Other names

FTH1P18FTHL18Ferritin heavy chain 1 pseudogene 18Ferritin, heavy polypeptide 1 pseudogene 18Ferritin, heavy polypeptide-like 18

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