Target intelligence / Profile preview

FTX transcript, XIST regulator conserved region 1 (FTX)

Target
FTX
Molecular classification
Non-coding RNA, Long non-coding RNA (lncRNA), Regulatory RNA
01

Overview

The FTX transcript, encoded by ENSG00000278421, is a long non-coding RNA that contains a region highly conserved in the regulation of XIST, which plays a role in X chromosome inactivation in eukaryotes[1][3]. As a non-coding RNA, it is not a protein nor a typical therapeutic target and is not currently linked to drug action, disease indications, or clinical biomarker use. Its main recognized function is epigenetic regulation, specifically acting as a positive regulator of XIST expression—a process essential for the regulation of gene dosage in female mammals. No evidence is available for its involvement in direct disease associations, drug interaction, or utility as a biomarker. The entry does not correspond to a classical drug target and should be marked as incorrect for contexts expecting a therapeutic drug target molecule such as a receptor or enzyme[1][3].

Other names
FTXFTX_1 misc RNA
02

Biological functions

Regulation of XIST (X-inactive specific transcript)Epigenetic regulationPotential involvement in X chromosome inactivation

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