Glucosaminyl (N-acetyl) transferase family member 7 (GCNT7)

GCNT7 (Glucosaminyl (N-acetyl) transferase family member 7) is a protein-coding gene encoding an enzyme predicted to enable acetylglucosaminyltransferase activity, specifically the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to acceptor substrates during protein glycosylation[1][2][3][6]. This enzyme is primarily localized to the Golgi membrane and is involved in the biosynthesis and branching of complex glycans, which are essential for protein folding, stability, and function[1][2][3][6]. GCNT7 belongs to the glycosyltransferase 14 family and plays a functional role in cell adhesion, cell signaling, and immune response, with aberrant expression implicated in cancer progression, congenital glycosylation disorders, and immune dysfunction[1][2][3][5][6]. No known drug interactions, biomarkers, or specific safety concerns have been reported for this target.

Other names

GCNT7C20orf105Probable beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7dJ1153D9.2