Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 pseudogene 2 (QRSL1P2)

QRSL1P2 is a pseudogene in humans, officially designated as "glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 pseudogene 2" and also referred to as QRSL1P2. Pseudogenes are genomic DNA sequences similar to known genes but are non-functional, usually due to mutations or lack of regulatory elements necessary for expression. QRSL1P2 is named for its homology to the functional gene QRSL1, which encodes a subunit of the mitochondrial glutaminyl-tRNA amidotransferase complex, but QRSL1P2 itself does not produce an active protein product and does not possess known biological, clinical, or pharmacological activity. Accordingly, it is not considered a valid therapeutic target, nor are there known disease associations, interacting drugs, biological processes, or molecular functions described for this pseudogene. QRSL1P2 is specifically listed as a pseudogene by authoritative sources including GeneCards and NCBI, with no evidence of protein-coding function or disease relevance. It is distinct from its protein-coding paralog QRSL1, which is involved in mitochondrial protein translation through the formation of correctly charged glutaminyl-tRNA(Gln), but this activity does not apply to the pseudogene. No information is available regarding QRSL1P2 as a therapeutic target, nor is it implicated in any pathway, disease, or as a drug target.

Other names

QRSL1P2