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Grass Pollen Allergens (Phleum pratense): Phl p 1, Phl p 2, Phl p 3, Phl p 5
- Molecular classification
- Glycoprotein (Phl p 1), Protein (Phl p 5), Allergen
01
Overview
Grass pollen allergens, including Phl p 1, Phl p 2, Phl p 3, and Phl p 5, are a group of proteins found in the pollen of grasses such as timothy grass (*Phleum pratense*). These allergens trigger allergic diseases like allergic rhinitis and asthma. Phl p 1 and Phl p 5 are major allergens, while Phl p 2 and Phl p 3 are less prevalent. They are localized in the cytoplasm and outer layer of grass pollen grains and become bioavailable upon hydration.
- Other names
- Timothy Grass Pollen AllergensPhl p 1Phl p 2Phl p 3Phl p 5Phl p 5b
02
Biological functions
AllergenImmune response elicitationIgE bindingEffector cell activation
03
Disease associations
Allergic rhinitis (hay fever)AsthmaAllergy
04
Safety considerations
Allergenicity
05
Biomarkers
Phl p 1 (allergy diagnosis)Phl p 5 (allergy diagnosis, symptom severity)
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